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Carrico Research Group
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Rubino, F.; Oum, H. Y.; Rajaram, L. Chu, Y.; Carrico, I. S.; (2012) Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry. JoVE, 66, e4246.

 

•Oum, H. Y.; Carrico, I. S.; (2012) Targeting adenovirus via chemoselective modification with affibodies. Bioconj. Chem. 23, 1370-1376.

 

•Nagarajan, S.; Taskent-Sezgin, H.; Parul, D.; Carrico, I.; Raleigh, D.; Dyer, R.; (2011) Differential ordering of the protein backbone and side chains during protein folding revealed by site-specific recombinant infrared probes. JACS, 133, 20335-20340.

 

•Banerjee, P. S.; Oum H. Y.; Carrico, I. S.: (2011) Dual functionalization of oncolytic adenoviral vectors allows targeting combination therapy. Bioorg. Med. Chem. Lett. 29, 4985-4988.

 

•Banerjee, P. S.; Ostapachuk, P.; Hearing, P.; Carrico, I. S.; (2011) Unnatural amino acidincorporation allows chemoselective modification and subsequent targeting of hAd5. J. Virol., 85, 7546-7554.

 

•Banerjee, P.S.; Carrico, I. S.; (2011) Chemoselective modification of viral proteins bearing metabolically introduced “clickable” amino acids and sugars. In Methods in Molecular Biology: Bioconjugation Protocols, 2nd ed., p. 55-67. Mark, S. S. ed. New York: Humana Press, 2011

 

•Boyce, M.; Carrico, I. S.; Ganguli, A.; Yu, S.; Hangauer, M.; Hubbard, S. C.; Kohler, J. J.; Bertozzi, C. R. (2011) Metabolic crosstalk allows labeling of O-linked β-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. PNAS, 108, 3141-3146.

 

•Carrico, I. S.; Francis, M. B.; (2010) New Frotiers in Bioconjugation. Curr. Op. Chem. Biol. 14, 771-773

 

•Banerjee, P. S.; Ostapachuk, P.; Hearing, P.; Carrico, I. S.; (2010) Chemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells.  JACS, 132, 13615-13617.

oResearch Highlighted in ACS Chem. Biol. (2010) 5, 1005-1006.

 

•Taskent-Sezgin, H.; Chung, J.; Banerjee, P. S.; Sureshbabu, N.; Dyer, R. B.; Carrico, I. S.; Raleigh, D. P.; (2010) Azidohomoalanine Provides a Conformationally Sensitive IR Probe of Protein Folding, Protein Structure and Electrostatics Which Can Be Readily Incorporated into Proteins. Angew. Chem. Int. Eng. Ed. 49, 7473-7475.

 

•Banerjee, P.S.; Carrico, I. S.; (2011) Chemoselective modification of viral proteins bearing metabolically introduced “clickable” amino acids and sugars.  Methods in Molecular Biology: Bioconjugation Protocols, 2nd ed.. Vol. 751, 55-67.

 

•Taskent-Sezgin, H.; Chung, J.; Patsalo, V.; Miyake-Stoner, S. J.; Miller, A. M.; Brewer, S. H.; Mehl, R. A.; Green, D. F.; Raleigh, D. P.; Carrico, I. S. (2009) Interpretation of p-Cyanophenylalanine Fluorescence in Proteins in Terms of Solvent Exposure and Contribution of Side-Chain Quenchers: A Combined Fluorescence, IR and Molecular Dynamics Study. Biochem. 48, 9040-9046.

 

•Carrico, I. S.; Kirshenbaum, K. (2009) Designer labels for virus coats. Nat. Nano. 4, 14-15.

 

•Carrico, I. S. (2008) A cysteine protease that cuts and pastes. Nat. Chem. Biol. 4, 525-526.

 

•Carrico, I. S. (2008) Chemoselective protein modification: hitting the target. Chem. Soc. Rev. 37, 1423-1431.

 

•Carrico, I. S.; Carlson, B.; Bertozzi, C. R. (2007) A genetically encodable aldehyde-tag for site-specific protein modification. Nat. Chem. Biol. 3, 321-322.

 

•Carrico, I. S.; Ganguli, A.; Bertozzi, C. R. (2008) Proteomic profiling of glycoproteome subclasses with metabolic labeling.  In preparation.

 

•Laughlin, S. T.; Agard, N. A.; Baskin, J. M.; Carrico, I. S.; Chang, P. V.; Ganjuli, A. S.; Hangauer, M. J.; Lo, A.; Prescher, J. A.; Bertozzi, C. R. (2006) Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Meth. Enz. 415, 230-250. 

 

•Carrico, I. S.; Heilshorn, S. A.; Mock, M. L.; Franck, C.; Ravichandran, G.; Tirrell, D. A. (2007) Lithographic patterning of intrinsically photoreactive cell-adhesive proteins.  J. Am. Chem. Soc. 129, 4874-4875.

 

•Wang, P.; Carrico, I. S.; Kirshenbaum, K.; Tang, Y.; Datta, D.; Mayo, S. L.; Tirrell, D. A. (2007) Engineering relaxed substrate specificity in E. coli phenylalanyl-tRNA synthetase to incorporate a diverse set of non-natural amino acids.  Submitted to Biochemistry.

 

•Datta, D.; Wang, P.; Carrico, I. S.; Mayo, S. L.; Tirrell, D. A. (2002) A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins.  J. Am. Chem. Soc. 124, 5652-5653.

 

•Kirshenbaum, K.; Carrico, I. S.; Tirrell, D. A. (2002) Biosynthesis of proteins incorporating a versatile set of phenylalanine analogs.  ChemBioChem. 3, 235-237.

 

•Pierce, D.A.; Jotterand, N.; Carrico, I.S.; Imperiali, B. (2001) Derivatives of 8-hydroxy-2-methylquinoline are powerful prototypes for zinc sensors in biological systems.  J. Am. Chem. Soc. 123, 5160-5161.

 

•Lipshutz, B. H.; James, B.; Vance, S.; Carrico, I. S. (1997) A potentially general intramolecular biaryl coupling approach to optically pure 2,2’-BINOL analogs.  Tet. Let. 38, 753-756.